17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: BEFORE Sum of Mean Source DF Squares Square F Value Pr > F Model 2 72.86666667 36.43333333 1.66 0.2092 Error 27 593.00000000 21.96296296 Corrected Total 29 665.86666667 R-Square C.V. Root MSE BEFORE Mean 0.109431 43.66273 4.6864659 10.733333 Source DF Type I SS Mean Square F Value Pr > F DRUG 2 72.86666667 36.43333333 1.66 0.2092 Source DF Type III SS Mean Square F Value Pr > F DRUG 2 72.86666667 36.43333333 1.66 0.2092 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 2 293.60000000 146.80000000 3.98 0.0305 Error 27 995.10000000 36.85555556 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.227826 76.84655 6.0708777 7.9000000 Source DF Type I SS Mean Square F Value Pr > F DRUG 2 293.60000000 146.80000000 3.98 0.0305 Source DF Type III SS Mean Square F Value Pr > F DRUG 2 293.60000000 146.80000000 3.98 0.0305 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Level of ------------BEFORE----------- ------------AFTER------------ DRUG N Mean SD Mean SD A 10 9.3000000 4.76211904 5.3000000 4.64399254 B 10 10.0000000 5.24933858 6.1000000 6.15449249 C 10 12.9000000 3.95671019 12.3000000 7.14998057 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 871.49740304 290.49913435 18.10 0.0001 Error 26 417.20259696 16.04625373 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.676261 50.70604 4.0057775 7.9000000 Source DF Type I SS Mean Square F Value Pr > F BEFORE 1 802.94369243 802.94369243 50.04 0.0001 DRUG 2 68.55371060 34.27685530 2.14 0.1384 Source DF Type III SS Mean Square F Value Pr > F BEFORE 1 577.89740304 577.89740304 36.01 0.0001 DRUG 2 68.55371060 34.27685530 2.14 0.1384 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Least Squares Means DRUG AFTER Std Err Pr > |T| LSMEAN LSMEAN LSMEAN H0:LSMEAN=0 Number A 6.7149635 1.2884943 0.0001 1 B 6.8239348 1.2724690 0.0001 2 C 10.1611017 1.3159234 0.0001 3 Pr > |T| H0: LSMEAN(i)=LSMEAN(j) i/j 1 2 3 1 . 0.9521 0.0793 2 0.9521 . 0.0835 3 0.0793 0.0835 . NOTE: To ensure overall protection level, only probabilities associated with pre-planned comparisons should be used. 17:43 Wednesday, March 8, 1995 Plot of AFTER*BEFORE. Symbol is value of DRUG. Plot of PAFTER*BEFORE. Symbol used is '*'. AFTER | 25 + | | C | | | 20 + C * | | C B | | | C 15 + * * | B * | A C | * | C * | A * * 10 + C * | B B | A A * | | * * | A * 5 + C C | A B * | B * | * | A B * | B A C B * 0 + A B A | * | | | | -5 + ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+-- 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 BEFORE NOTE: 11 obs hidden. 17:43 Wednesday, March 8, 1995 Plot of RAFTER*PAFTER. Symbol is value of DRUG. RAFTER | | 10.0 + | | | C | 7.5 + C | A | | | 5.0 + B | C | B | | 2.5 + C | A | | A A A | 0.0 + B B B B | | A A B | | B A B -2.5 + C C | B | C C | A A | -5.0 + | C | | C | -7.5 + | ---+----------+----------+----------+----------+----------+----------+-- -5 0 5 10 15 20 25 PAFTER 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 2 293.60000000 146.80000000 3.98 0.0305 Error 27 995.10000000 36.85555556 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.227826 76.84655 6.0708777 7.9000000 Source DF Type I SS Mean Square F Value Pr > F DRUG 2 293.60000000 146.80000000 3.98 0.0305 Source DF Type III SS Mean Square F Value Pr > F DRUG 2 293.60000000 146.80000000 3.98 0.0305 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: RAFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 1 514.65732879 514.65732879 29.99 0.0001 Error 28 480.44267121 17.15866683 Corrected Total 29 995.10000000 R-Square C.V. Root MSE RAFTER Mean 0.517192 9999.99 4.1423021 0.0000000 Source DF Type I SS Mean Square F Value Pr > F BEFORE 1 514.65732879 514.65732879 29.99 0.0001 Source DF Type III SS Mean Square F Value Pr > F BEFORE 1 514.65732879 514.65732879 29.99 0.0001 T for H0: Pr > |T| Std Error of Parameter Estimate Parameter=0 Estimate INTERCEPT -9.436263516 -5.01 0.0001 1.88166150 BEFORE 0.879154986 5.48 0.0001 0.16052702 17:43 Wednesday, March 8, 1995 Plot of RAFTER*BEFORE. Symbol is value of DRUG. Plot of PRAFTER*BEFORE. Symbol used is '*'. RAFTER | 15 + | | | | B | C 10 + | * | | A C B * | * | C A 5 + * | * | C | B A A B * | * | A C * 0 + C * | * | A * | B C * | A B * | B * -5 + A B A * | B | * | C C | | -10 + | | C | | | -15 + ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+-- 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 BEFORE NOTE: 16 obs hidden. 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 1 802.94369243 802.94369243 46.28 0.0001 Error 28 485.75630757 17.34843956 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.623065 52.72336 4.1651458 7.9000000 Source DF Type I SS Mean Square F Value Pr > F BEFORE 1 802.94369243 802.94369243 46.28 0.0001 Source DF Type III SS Mean Square F Value Pr > F BEFORE 1 802.94369243 802.94369243 46.28 0.0001 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C PAFTER 16 10.38906688 9.290949139 -0.592110533 1.6041249499 11.487184622 12.585302363 13.683420104 15.879655587 16.977773328 19.174008811 2.7022426912 3.8003604325 4.8984781738 5.9965959151 7.0947136564 8.1928313977 Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: RAFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 2 61.25605285 30.62802642 1.95 0.1621 Error 27 424.50025472 15.72223166 Corrected Total 29 485.75630757 R-Square C.V. Root MSE RAFTER Mean 0.126104 -9999.99 3.9651269 -0.0000000 Source DF Type I SS Mean Square F Value Pr > F DRUG 2 61.25605285 30.62802642 1.95 0.1621 Source DF Type III SS Mean Square F Value Pr > F DRUG 2 61.25605285 30.62802642 1.95 0.1621 17:43 Wednesday, March 8, 1995 Plot of RAFTER*PAFTER. Symbol is value of DRUG. Plot of MRAFTER*PAFTER. Symbol used is '*'. RAFTER | | 12.5 + | | | C 10.0 + C | | | 7.5 + | C | | A 5.0 + | B | C | 2.5 + | B * * * * * * * | A | A A 0.0 + A | B B B B C C | C * * * * * * * * * * * | A C -2.5 + B C A | B | B A B | C -5.0 + A | | A | -7.5 + | -+-------------+-------------+-------------+-------------+-------------+ -5 0 5 10 15 20 PAFTER NOTE: 12 obs hidden. 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 871.49740304 290.49913435 18.10 0.0001 Error 26 417.20259696 16.04625373 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.676261 50.70604 4.0057775 7.9000000 Source DF Type I SS Mean Square F Value Pr > F DRUG 2 293.60000000 146.80000000 9.15 0.0010 BEFORE 1 577.89740304 577.89740304 36.01 0.0001 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 871.49740304 290.49913435 18.10 0.0001 Error 26 417.20259696 16.04625373 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.676261 50.70604 4.0057775 7.9000000 Source DF Type I SS Mean Square F Value Pr > F BEFORE 1 802.94369243 802.94369243 50.04 0.0001 DRUG 2 68.55371060 34.27685530 2.14 0.1384 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 871.49740304 290.49913435 18.10 0.0001 Error 26 417.20259696 16.04625373 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.676261 50.70604 4.0057775 7.9000000 Source DF Type III SS Mean Square F Value Pr > F BEFORE 1 577.89740304 577.89740304 36.01 0.0001 DRUG 2 68.55371060 34.27685530 2.14 0.1384 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: AFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 882.63946368 294.21315456 18.84 0.0001 Error 26 406.06053632 15.61771294 Corrected Total 29 1288.70000000 R-Square C.V. Root MSE AFTER Mean 0.684907 50.02437 3.9519252 7.9000000 Source DF Type I SS Mean Square F Value Pr > F BEFORE*DRUG 3 882.63946368 294.21315456 18.84 0.0001 Source DF Type III SS Mean Square F Value Pr > F BEFORE*DRUG 3 882.63946368 294.21315456 18.84 0.0001 17:43 Wednesday, March 8, 1995 Plot of AFTER*BEFORE. Symbol is value of DRUG. AFTER | | 23 + C 22 + 21 + 20 + C 19 + 18 + C B 17 + 16 + C 15 + 14 + B 13 + A C 12 + C 11 + A 10 + C 9 + B B 8 + A A 7 + 6 + A 5 + C C 4 + A B 3 + B 2 + A B 1 + B A C B 0 + A B A | ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+-- 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 BEFORE 17:43 Wednesday, March 8, 1995 Plot of PAFTER*BEFORE. Symbol used is '*'. PAFTER | 25 + | | | | * | 20 + | | | | | * 15 + * | * | * | * | | * * 10 + * | * | | * | * | * 5 + * | * | * | * | * | * 0 + | * | | | | -5 + | ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+-- 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 BEFORE NOTE: 10 obs hidden. 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Class Level Information Class Levels Values DRUG 3 A B C Number of observations in data set = 30 17:43 Wednesday, March 8, 1995 General Linear Models Procedure Dependent Variable: RAFTER Sum of Mean Source DF Squares Square F Value Pr > F Model 3 6.28077414 2.09359138 0.13 0.9399 Error 26 410.92182282 15.80468549 Corrected Total 29 417.20259696 R-Square C.V. Root MSE RAFTER Mean 0.015054 -9999.99 3.9755107 -0.0000000 Source DF Type I SS Mean Square F Value Pr > F PAFTER*DRUG 3 6.28077414 2.09359138 0.13 0.9399 Source DF Type III SS Mean Square F Value Pr > F PAFTER*DRUG 3 6.28077414 2.09359138 0.13 0.9399 17:43 Wednesday, March 8, 1995 Plot of RAFTER*PAFTER. Symbol is value of DRUG. Plot of PRAFTER*PAFTER. Symbol used is '*'. RAFTER | 10.0 + | | | C | 7.5 + C | A | | | 5.0 + B | C | B | | 2.5 + C | A | | A A A | * * * * 0.0 + B B B B * **** * * * * * * * * | * * * | A A B * | * | B A B -2.5 + C C | B | C C | A A | -5.0 + | C | | C | -7.5 + | ---+----------+----------+----------+----------+----------+----------+-- -5 0 5 10 15 20 25 PAFTER NOTE: 8 obs hidden.